Manhattan Scientifics Files Form 8-K Describing Recent Milestone Payment

November 1, 2010

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NEW YORK--Manhattan Scientifics Inc. (OTCBB: MHTX), a nanomedicine technology transfer and commercialization pioneer, announced today that it has filed a Current Report on Form 8-K with the Securities Exchange Commission describing the terms of the company's recent milestone payment.

Manhattan Scientifics received a $1 million milestone payment from Carpenter Technologies, Inc. (CRS), the company's collaborative partner on nanometals technology for satisfying its performance obligations under the Technology Transfer Agreement between the parties dated August 12, 2009.

At a recent press conference the company also announced the official start of its production and sales of nanostructured titanium dental implants. The press conference is now available for viewing at the company's website and at the following link, http://www.mhtx.com/press-conference.htm.

About Manhattan Scientifics

Manhattan Scientifics, Inc. (www.mhtx.com) is located in New Mexico, New York and Montreal. It is focused on technology transfer and commercialization of disruptive technologies in the nano medicine space. The company is presently developing commercial medical prosthetics applications for its ultra-fine grain metals and plans to commercialize the cancer research work and nano medical applications developed by Senior Scientific LLC, a unit of the Company.

Forward-looking statement

This press release contains forward-looking statements. Such forward-looking statements are subject to a number of risks, assumptions and uncertainties that could cause the Company's actual results to differ materially from those projected in such forward-looking statements. Forward-looking statements speak only as of the date made and are not guarantees of future performance. We undertake no obligation to publicly update or revise any forward-looking statements.